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Sex-Specific Imaging Signatures and Disease Progression

January 29, 2026

What this project does

Identifies imaging patterns that differ between women and men and examines how these relate to clinical outcomes.

Why it matters clinically

Sex differences in brain pathology may explain variation in symptoms, disease progression, and treatment response.

Key activities

  • Analyze sex-based differences in tau burden, neurodegeneration, and vascular co-pathology
  • Integrate imaging with immune, vascular, and α-synuclein biomarkers
  • Evaluate relationships between imaging findings and cognitive trajectories

What will be delivered

  • Sex-specific imaging signatures
  • Imaging-based markers of progression and risk

Who this helps

  • Clinicians seeking biologically informed prognostic tools
  • Researchers developing sex-informed diagnostic strategies