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Clinicopathologic and Biomarker Validation

January 29, 2026

What this project does

Links imaging findings with post-mortem pathology and fluid biomarkers to validate imaging measures.

Why it matters clinically

Validation against pathology strengthens confidence in imaging as a surrogate marker of underlying disease biology.

Key activities

  • Collaborate with the Neuropathology Core to confirm imaging–pathology relationships
  • Guide tissue sampling based on imaging findings
  • Integrate imaging data with biomarker profiles

What will be delivered

  • Validated imaging biomarkers
  • Strong clinicopathologic correlation datasets

Who this helps

  • Clinicians interpreting imaging results
  • Researchers validating biomarkers for clinical trials