Recruitment and Longitudinal Follow-Up of a Diverse ADRD Cohort

What this project does
Recruits and follows a longitudinal cohort of cognitively unimpaired and mildly impaired older adults representative of the Houston population.

Why it matters clinically
Longitudinal, well-characterized cohorts are essential for understanding disease progression, identifying early changes, and evaluating potential interventions.

Key activities
-Recruit 400 participants aged 60–85 (100 cognitively unimpaired, 300 with MCI)
-Ensure equal representation of women and men
-Recruit at least 50% of participants from underrepresented racial and ethnic groups
-Conduct annual evaluations at a single clinical site for consistency
-Provide bilingual assessments in English and Spanish

What will be delivered
-A stable, diverse, longitudinal clinical cohort
-High-quality annual clinical datasets linked across cores

Who this helps
-Clinicians and investigators studying ADRD progression
-Researchers seeking representative cohorts for discovery and validation