Comprehensive Clinical and Cognitive Phenotyping

What this project does
Performs standardized baseline and annual clinical evaluations using validated assessment batteries.

Why it matters clinically
Consistent, detailed phenotyping allows accurate diagnosis, staging, and longitudinal tracking of cognitive and functional change.

Key activities
-Complete baseline and annual UDS v4 and LBD v3.1 visits
-Collect detailed medical, vascular, and neurological histories
-Capture sex-specific factors, including reproductive and hormonal histories
-Assess Lewy body disease features using validated tools

What will be delivered
-Harmonized clinical datasets compatible with national ADRC standards
-Detailed phenotypes supporting subtype and progression analyses

Who this helps
-Clinicians interpreting symptom trajectories
-Researchers studying heterogeneity and co-pathology